What day is considered to be the first day of a female’s reproductive cycle?

What day is considered to be the first day of a female’s reproductive cycle?
a. When hormone levels are low and the uterus lining is shed.
b. When hormone levels are high and the uterus lining is shed.
c. When hormone levels are low and the ovary releases an egg.
d. When hormone levels are high and the ovary releases an egg.