How do human beings influence the ecology of a region?

How do human beings influence the ecology of a region? Explain.

Due to the excessive exploitation of the plant and animal resources by human beings, the ecosystem has been disturbed.
The greed of human beings leads to over-utilisation of natural resources. They cut the trees and kill animals, creating ecological imbalance.
As a result, some of the plants and animals have reached the verge of extinction.