Differences between chordates and non-chordates are given below.
Chordates :
Notocord is present at least in some stages of development.
Central nervous system is dorsal, hollow, single and non-ganglionated.
Gill slits present on lateral side of pharynx in sum stages or throughout life.
Tail is present in some stages and throughout life
Heart is ventral.
Haemoglobin is present in RBCs.
Non-Chordates :
Noto chord is absent.
Central nervous system is ventral, solid, double and gangliolated.
Gill slits are absent.
Tail generally absent.
Heart is dorsal.
It is present in plasma.