Write the type and location of the gene causing thalassemia in humans.State the cause and symptoms of the disease
CBSE Class 12
CBSE Class 12 Biology
2016-08-29 10:50:33 UTC
Autosomal, recessive gene, gene for alpha thalassaemia is on chromosome 16, for Beta thalassaemia it is on chromosome 11.
Cause of symptoms - Mutation or deletion of the gene/genes, resulting in reduced rate of synthesis of one of the globin chains/ alpha or beta chains.
Thalassaemia is a quantitative problem/of too few globin molecules of haemoglobin, while sickle cell is a qualitative problem of synthesizing an incorrectly functioning globin.