The kidneys are considered as master chemists of the body.
(a) If they are damaged, it would disturb the normal functioning of the life processes.
(b) Due to the effect of toxins produced by some bacteria the filters of tiny uriniferous tubules are damaged.
(c) They become perforated with larger holes and
allow blood cells, and proteins to pass through them along with the urea and water during filtration of blood in formation of urine.