When the blood supply to myocardium of the heart is greatly reduced, then the cardiac muscle fibres die. This reduced blood supply can be due to the blockage of the coronary muscles by the thrombus (blood clot formed in the coronary artery).
When the blood supply to myocardium of the heart is greatly reduced, then the cardiac muscle fibres die. This reduced blood supply can be due to the blockage of the coronary muscles by the thrombus (blood clot formed in the coronary artery).