Explain the statement by giving two examples : 'It is not necessary that the pathogen may affect an organ or tissue depending upon the point of entry.'

(a) AIDS causing virus-enter through sex organs - spread to lymph modes all over the body.
(b) Japanese encephalitis - virus - enter blood through mosquito bite - reaches brain.
© Malaria- protozoa plasmodium- enter blood through mosquito bite - reaches liver and then passes into the RBC.